Covid Infection May Impact Semen Quality In Men: AIIMS Study 

Delhi/Hyderabad, Jan 5 (Maxim News)  Infection with the SARS-CoV-2 virus may negatively impact semen quality, according to a study on 30 males conducted by researchers at the All India Institute of Medical Sciences (AIIMS) 

The team led by researchers at AIIMS Patna noted that Covid-19 can lead to multiorgan damage through the angiotensin-converting enzyme-2 receptor (ACE2), abundant in testicular tissue. 

ACE2 acts as the receptor for the SARS-CoV-2 spike protein, through which the virus gains entry into the host cells.  Shedding of SARS-CoV-2 in semen — the thick, white fluid that contains sperm — and its impact on sperm formation and fertility potential.  The study, published in the Cureus Journal of Medical Science, investigated the presence of SARS-CoV-2 in the semen of Covid-19 males. 

The researchers also analyzed the effect of the disease on semen quality and sperm DNA fragmentation index, which reflects the integrity of and the damage to the DNA, thereby detecting potential sperm damage.  Thirty Covid-19 male patients aged 19-45 registered at AIIMS Patna hospital participated in the study between October 2020 and April 2021. 

The study, including researchers from AIIMS Mangalagiri and AIIMS New Delhi, found that all semen samples collected in the first and second sampling tested with real-time reverse transcription-polymerase chain reaction (RT-PCR) were negative for SARS-CoV-2. 

In the first sampling, semen volume, vitality, total motility, sperm concentration, and total sperm count were significantly lower, the researchers said.  (Maxim News) 

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